| Identification | Back Directory | [Name]
BENZP-DINITRIDE-THIO-KETONE | [CAS]
4547-02-8 | [Synonyms]
Thionordiazepam
Alprazolam Impurity 17
BENZP-DINIRIDE-THIO-KETONE
BENZP-DINITRIDE-THIO-KETONE
Benzodiazepines Intermediate 1
7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H)
7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H)-thione
7-chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepine-2-thione
2H-1,4-Benzodiazepine-2-thione, 7-chloro-1,3-dihydro-5-phenyl- | [Molecular Formula]
C15H11ClN2S | [MDL Number]
MFCD02068928 | [MOL File]
4547-02-8.mol | [Molecular Weight]
286.78 |
| Chemical Properties | Back Directory | [Melting point ]
256-258?C (dec.) | [Boiling point ]
408.9±55.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
9.72±0.40(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia. |
|
|