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457-60-3

457-60-3 Structure

457-60-3 Structure
IdentificationBack Directory
[Name]

Neoarsphenamine
[CAS]

457-60-3
[Synonyms]

914
arsevan
Novarsan
miarsenol
Ai3-14551
collunovar
collunover
neo-i.c.i.
novarsenol
neoarsoluin
neosalvarsan
neoarsfenamin
Vetarsenobillon
NEOARSPHENAMINE
novarsenobenzol
novarsenobillon
Neoarsphenaminum
Einecs 207-273-7
Neo-gargarol liquidum
Neoarsphenamine USP/EP/BP
amino)methyl)ester,monosodiumsalt
arsphenaminemethylenesulfoxylicacidsodiumsalt
3,3’-diamino-4,4’-dihydroxyarsenobenzenemethylenesulfoxylatesodium
((5-(3-amino-4-hydroxyphenyl)arseno)-2-hydroxyanilino)methanolsulfoxylateso
sulfoxylicacid,mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)
((5-(3-Amino-4-hydroxyphenyl)arseno)-2-hydroxyanilino)methanol sulfoxylate sodium
sodium,[5-(3-amino-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyanilino]methanesulfinate
Sodium [[5-(3-amino-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyphenyl]amino]methanesulfinate
[EINECS(EC#)]

207-273-7
[Molecular Formula]

C13H13As2N2NaO4S
[MDL Number]

MFCD00864841
[MOL File]

457-60-3.mol
[Molecular Weight]

466.15
Chemical PropertiesBack Directory
[Uses]

Treatment against syphilis.
[CAS DataBase Reference]

457-60-3
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[Safety Statements ]

24/25-36
[Safety Profile]

Poison by intravenous and subcutaneous routes. When heated to decomposition it emits very toxic fumes of As, , NOx, Na2O,and SOx,. See also ARSENIC COMPOUNDS.
[Toxicity]

guinea pig,LDLo,intraperitoneal,75mg/kg (75mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 9, Pg. 354, 1917.
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium formaldehydesulfoxylate dihydrate-->arsenobenzene
Hazard InformationBack Directory
[Description]

Neosalvarsan (compound 914) is a salt derivative of Salvarsan and is water soluble, which showed reduced side effects .Later work showed that neither Salvarsan nor Neosalvarsan was the active pharmaceutical ingredient (API).
[Chemical Properties]

Yellow powder or granules. Easily oxidized in air, accelerated by high temperatures. Soluble in water, insoluble in ethanol, chloroform, and ether.
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