ChemicalBook--->CAS DataBase List--->465-11-2

465-11-2

465-11-2 Structure

465-11-2 Structure
IdentificationBack Directory
[Name]

GAMABUFOTALIN
[CAS]

465-11-2
[Synonyms]

Gamabufagin
Gamabufogenin
GAMABUFOTALIN
GAMABUFOTALIN USP/EP/BP
GAMABUFOTALIN 465-11-2
Gamabufotalin (Gamabufagin)
3,11,14-Trihydroxybufa-20,22-dienolide
3β,11α,14-Trihydroxy-5β-bufa-20,22-dienolide
Bufa-20,22-dienolide,3,11,14-trihydroxy-, (3b,5b,11a)-
Bufa-20,22-dienolide, 3,11,14-trihydroxy-, (3β,5β,11α)-
22-dienolide,3-beta,11-alpha,14-trihydroxy-5-beta-bufa-2
5beta-Bufa-20,22-dienolide, 3beta,11alpha,14-trihydroxy-
3-beta,11-alpha,14-Trihydroxy-5-beta-bufa-20,22-dienolide
22-dienolide,3,11,14-trihydroxy-,(3-beta,5-beta,11-alpha)-bufa-2
Bufa-20,22-dienolide, 3,11,14-trihydroxy-, (3beta,5beta,11alpha)-
5-[(3S,5R,8R,9S,10S,11R,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one
5-[(3S,5R,8R,9S,10S,11R,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-pyranone
[Molecular Formula]

C24H34O5
[MDL Number]

MFCD01740822
[MOL File]

465-11-2.mol
[Molecular Weight]

402.52
Chemical PropertiesBack Directory
[Melting point ]

254°
[alpha ]

D18 +1.26° (c = 0.793 in methanol)
[Boiling point ]

595.8±50.0 °C(Predicted)
[density ]

1.289±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

14.52±0.70(Predicted)
[color ]

White to off-white
[CAS DataBase Reference]

465-11-2
Hazard InformationBack Directory
[Description]

Gamabufotalin belongs to the bufastenolide compound contained in traditional Chinese medicine toadstool. Previous studies have shown that CS-6 has a good effect in inhibiting tumor cell growth and inflammatory response.
[Chemical Properties]

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from toad secretions.
[Uses]

Gamabufotalin has a strong heart and anti-tumor effect.
[Definition]

ChEBI:Gamabufogenin is a steroid lactone. It is functionally related to a bufanolide.
[Biological Activity]

Gamabufotalin (Gamabufagin), the main bufastenene in Bufonis bufa, is widely used in cancer research due to its stability and low toxicity.
Spectrum DetailBack Directory
[Spectrum Detail]

GAMABUFOTALIN(465-11-2)1HNMR
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