| Identification | More | [Name]
2-AMINO-3-CYANOTHIOPHENE | [CAS]
4651-82-5 | [Synonyms]
2-AMINO-3-CYANOTHIOPHENE
2-AMINO-3-THIOPHENECARBONITRILE
2-AMINOTHIOPHENE-3-CARBONITRILE
AKOS 92285
AKOS B014697
AKOS BBS-00006621
ART-CHEM-BB B014697
BUTTPARK 36\18-34
TIMTEC-BB SBB005484
2-AMINIO-3-CYANOTHIOPHENE | [Molecular Formula]
C5H4N2S | [MDL Number]
MFCD00706298 | [Molecular Weight]
124.16 | [MOL File]
4651-82-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
104-108 °C | [Boiling point ]
318℃ | [density ]
1.33 | [Fp ]
146℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
powder to crystalline | [pka]
-0.28±0.10(Predicted) | [color ]
White to Light yellow to Light orange | [CAS DataBase Reference]
4651-82-5(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
2-Aminothiophene-3-carboxynitrile is a pharmaceutical intermediate. Due to its important role in immunity, HPK1 inhibitors play an important role in malignant solid tumors or hematological malignancies (such as acute myeloid leukemia, bladder epithelial carcinoma, breast cancer, colon cancer, lung cancer, pancreatic cancer, melanoma), autoimmune diseases (such as systemic lupus erythematosus, psoriatic arthritis), and inflammatory responses. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R41:Risk of serious damage to eyes.
R37/38:Irritating to respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S39:Wear eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3439 | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2934999090 |
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