| Identification | Back Directory | [Name]
AMG 487 (S-enantiomer) | [CAS]
473720-30-8 | [Synonyms]
AMG 487 (S-enantiomer)
AMG 487 (Senantiomer),AMG 487 (S enantiomer)
Benzeneacetamide, N-[(1S)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-
N-?[(1S)?-?1-?[3-?(4-Ethoxyphenyl)?-?3,?4-?dihydro-?4-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl]?ethyl]?-?N-?(3-?pyridinylmethyl)?-?4-?(trifluoromethoxy)?-benzeneacetamide | [Molecular Formula]
C32H28F3N5O4 | [MDL Number]
MFCD30536209 | [MOL File]
473720-30-8.mol | [Molecular Weight]
603.59 |
| Chemical Properties | Back Directory | [Boiling point ]
750.0±70.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 150 mg/mL (248.51 mM) | [form ]
Solid | [pka]
4.66±0.11(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
N-?[(1S)?-?1-?[3-?(4-Ethoxyphenyl)?-?3,?4-?dihydro-?4-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl]?ethyl]?-?N-?(3-?pyridinylmethyl)?-?4-?(trifluoromethoxy)?-benzeneacetamide is a selective and potent antagonist of the chemokine receptor CXCR3. | [IC 50]
CXCR3 | [storage]
Store at -20°C |
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