| Identification | Back Directory | [Name]
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) | [CAS]
474922-20-8 | [Synonyms]
DSPE-PEG2000-COOH
DSPE-PEG-2K-CH2COOH
DSPE-PEG(2000) Carboxylic Acid
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt) | [Molecular Formula]
(C2H4O)nC44H84NO12P.H3N | [MOL File]
474922-20-8.mol |
| Chemical Properties | Back Directory | [solubility ]
Ethanol: Sparingly soluble: 1-10 mg/ml | [InChIKey]
MFOLYTNLQCGGBD-UHFFFAOYSA-N | [SMILES]
C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OCC(=O)O.N |
| Hazard Information | Back Directory | [Description]
DSPE-PEG-CH2COOH, MW 2,000 is a PEG polymer with DSPE and carboxylic acid end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The -COOH group can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond. | [Uses]
DSPE-PEG-Carboxylic Acid is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes[1]. | [References]
[1] Su H, et, al. A brightly red emissive AIEgen and its antibody conjugated nanoparticles for cancer cell targeting imaging. Materials Chemistry Frontiers. Issue 10, 2022. |
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