ChemicalBook--->CAS DataBase List--->475650-36-3

475650-36-3

Request For Quotation
475650-36-3 Structure

475650-36-3 Structure
IdentificationBack Directory
[Name]

Inarigivir (ORI-9020, SB-9000)
[CAS]

475650-36-3
[Synonyms]

SB-40
SB9000
ORI9020
ORI-9020
ORI 9020
Inarigivir
narigivir SB9000
inarigivir SB9000
Inarigivir (ORI-9020
Inarigivir (ORI-9020, SB-9000)
2'-O-Methyl-P-thiouridylyl-(3'→5')-2'-deoxyadenosine
2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoksyadenosine
INARIGIVIR; ORI-9020; ORI 9020; ORI9020; SB-40; SB-9000; SB9000; SB-9000
[Molecular Formula]

C20H26N7O10PS
[MDL Number]

MFCD31727872
[MOL File]

475650-36-3.mol
[Molecular Weight]

587.5
Chemical PropertiesBack Directory
[density ]

1.98±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

2.98±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

2''-O-Methyl-P-thiouridylyl-(3''→5'')-2''-deoxyadenosine, has identified to be the first orally bioavailable dinucleotide prodrugs for further therapeutic development against the hepatitis B virus (HBV).
[in vivo]

Inarigivir (100 mg/kg/day, ip) significantly reduces viral DNA in the liver and shows anti-HBV activity. Serum HBV DNA is not reduced in response to treatment. Inarigivir does not affect levels of HBV RNA in liver, levels of HBeAg in serum, or mean titers of HBsAg. The minimal effective dose is identified to be between 1.6 and 0.5 mg/kg/day using liver HBV DNA values[1].

Animal Model:Mice[1]
Dosage:100 mg/kg.
Administration:IP, daily.
Result:Significantly reduced viral DNA in the liver and shows anti-HBV activity similar ADV positive control.
[storage]

Store at -20°C
475650-36-3 suppliers list
Company Name: Nanjing Chemlin Chemical Co., Ltd  
Telephone: 025-83697070 13770331960
Website: www.echemlin.cn
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Telephone: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Telephone: 177-54423994 17754423994
Website: www.biochempartner.com
Company Name: Shanghai Rechem science Co., Ltd.  
Telephone: 021-31433387 15618786686
Website: http://cn.rechemscience.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Telephone: QQ：65489617 13301690235
Website: www.atkchemical.com/
Company Name: Amadis Chemical Company Limited  
Telephone: 571-89925085
Website: http://www.amadischem.com
Company Name: Heze Development Zone chuangli Chemical Co., Ltd.  
Telephone: 0530-+86-530-529 6766，+86-15666160102 15666160102
Website: https://www.chemicalbook.com/supplier/10660012/
Company Name: Twochem Co.Ltd.  
Telephone: 021-58111628 15800915896
Website: cn.twochem.com
Company Name: Tianjin Kaifu Pharmaceutical Technology Co., Ltd.  
Telephone: 18081075745
Website: www.chemicalbook.com/ShowSupplierProductsList31177/0_EN.htm
Company Name: NewCan Biotech Limited  
Telephone: +86-571-86912261 19975279805
Website: https://www.newcanbio.com/
Company Name: Suzhou Ruiyuanda New Materials Co., Ltd  
Telephone: 0510-15312278075 15312278075
Website: https://www.chemicalbook.com/ShowSupplierProductsList534904/0_EN.htm
Company Name: Chunchuang (Wuhan) Technology Co., Ltd  
Telephone: 15727060112
Website: www.chemicalbook.com/showsupplierproductslist1427518/0_en.htm
Company Name: cjbscvictory  
Telephone: 13348960310 13348960310
Website: www.weikeqi-biotech.com/
Company Name: Hubei Kele Fine Chemical Co., Ltd  
Telephone: 027-59101668 19945030958
Website: www.kerle.cn
Company Name: ChemeGen  
Telephone: 18818260767
Website: https://www.chemegen.com
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.  
Telephone: +86-027-59232304 15387063101
Website: https://www.yingnor.com/
Tags:475650-36-3 Related Product Information
475650-36-3 10527-48-7 942123-43-5