| Identification | Back Directory | [Name]
Eupaglehnin C | [CAS]
476630-49-6 | [Synonyms]
Eupaglehnin C
[(3aR,4R,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (Z)-2-(hydroxymethyl)but-2-enoate
2-Butenoic acid, 2-(hydroxymethyl)-, (3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2Z)- | [Molecular Formula]
C20H26O5 | [MOL File]
476630-49-6.mol | [Molecular Weight]
346.42 |
| Hazard Information | Back Directory | [Uses]
Eupaglehnin C is a germacrane-type sesquiterpenoi. Eupaglehnin C can be isolated from the MeOH extract of Eupatorium glehni (Compositae). Eupaglehnin C has cytotoxic activity against HeLa-S3 cancer cell lines[1][2]. | [References]
[1] Tori M, et al. Seven germacranolides, eupaglehnins A, B, C, D, E, and F, and 2alpha-acetoxyepitulipinolide from Eupatorium glehni. Chem Pharm Bull (Tokyo). 2002 Sep;50(9):1250-4. DOI:10.1248/cpb.50.1250
[2] Zhang ML, et al. Chemical constituents of plants from the genus Eupatorium. Chem Biodivers. 2008 Jan;5(1):40-55. DOI:10.1002/cbdv.200890014 |
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