| Identification | Back Directory | [Name]
2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- | [CAS]
478963-79-0 | [Synonyms]
CaSR-IN-10a
Calcium-sensing receptor antagonist 1
CalciuM-Sensing Receptor Antagonists I
1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-
1-(1-Methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-2(1H)-Quinazolinone
2(1H)-QUINAZOLINONE, 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)- | [Molecular Formula]
C23H24N2O2 | [MDL Number]
MFCD11977743 | [MOL File]
478963-79-0.mol | [Molecular Weight]
360.45 |
| Chemical Properties | Back Directory | [Boiling point ]
510.1±60.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Powder | [pka]
0.50±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Calcium-Sensing receptor antagonist I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263. |
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