| Identification | Back Directory | [Name]
ARTEMISETIN(P) | [CAS]
479-90-3 | [Synonyms]
ArteMitin
Erianthin
ARTEMISETIN(P)
Artemisetin, 98%, from Artemisia argyi
3,3',4',6,7-Pentamethoxy-5-hydroxyflavone
2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxychromen-4-one
2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-chromen-4-one
2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C20H20O8 | [MDL Number]
MFCD00800687 | [MOL File]
479-90-3.mol | [Molecular Weight]
388.37 |
| Chemical Properties | Back Directory | [Melting point ]
261～264℃ | [Boiling point ]
588.8±50.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: Soluble
Methanol: Soluble | [form ]
powder | [pka]
6.12±0.40(Predicted) | [color ]
Yellow | [Water Solubility ]
Slightly soluble in water | [Major Application]
food and beverages | [InChI]
InChI=1S/C20H20O8/c1-23-11-7-6-10(8-12(11)24-2)18-20(27-5)17(22)15-13(28-18)9-14(25-3)19(26-4)16(15)21/h6-9,21H,1-5H3 | [InChIKey]
RIGYMJVFEJNCKD-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(OC)C(OC)=C2)OC2=CC(OC)=C(OC)C(O)=C2C(=O)C=1OC | [LogP]
2.550 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Orange needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the aerial parts of wormwood, bitter wormwood, and stinky elixir. | [Uses]
Artemitin has an anti-tumor, anti-inflammatory, antibacterial, blood pressure lowering effects. | [Definition]
ChEBI: Artemetin is a member of flavonoids and an ether. | [Biological Activity]
Artemitin is a natural flavonoid found in Heliconia chinensis with antioxidant, anti-inflammatory, and antiviral effects. | [References]
[1] ALTON J. DUGAS JR. Evaluation of the Total Peroxyl Radical-Scavenging Capacity of Flavonoids: Structure−Activity Relationships[J]. Journal of Natural Products , 2000, 63 3: 327-331. DOI: 10.1021/np990352n
[2] M IQBAL CHOUDHARY. Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus.[J]. Phytotherapy Research, 2009, 23 9: 1336-1339. DOI: 10.1002/ptr.2639
[3] K C LIU. Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures.[J]. Plant Cell Reports, 1992, 11 12: 637-640. DOI: 10.1007/bf00236389
[4] W.G KO. Polymethoxyflavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells[J]. Food and Chemical Toxicology, 2000, 38 10: Pages 861-865. DOI: 10.1016/s0278-6915(00)00079-x
[5] PRISCILA DE SOUZA . Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats[J]. Phytomedicine, 2011, 18 10: Pages 819-825. DOI: 10.1016/j.phymed.2011.02.005 |
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