| Identification | Back Directory | [Name]
(3R)-8-hydroxy-3-methyl-isochroman-1-one | [CAS]
480-33-1 | [Synonyms]
(R)-()-Mellein
(R)-(-)-Mellein, (S)-(+)-Mellein
(3R)-8-hydroxy-3-methyl-isochroman-1-one
(R)-3,4-Dihydro-3-methyl-8-hydroxyisocoumarin
[R,(-)]-3,4-Dihydro-3α-methyl-8-hydroxyisocoumarin
(R)-3,4-Dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C10H10O3 | [MDL Number]
MFCD22199813 | [MOL File]
480-33-1.mol | [Molecular Weight]
178.18 |
| Chemical Properties | Back Directory | [Melting point ]
58-58.5 °C | [Boiling point ]
392.7±42.0 °C(Predicted) | [density ]
1.252±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | [form ]
A crystalline solid | [pka]
9.86±0.40(Predicted) | [color ]
White to off-white | [CAS DataBase Reference]
480-33-1 |
| Hazard Information | Back Directory | [Uses]
(R)-(?)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(?)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 μM.[Cayman Chemical] | [storage]
Store at -20°C |
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