| Hazard Information | Back Directory | [Description]
GKA-22 is an allosteric activator of human glucokinase in the absence of glucose. | [Uses]
Glucokinase activator 6 (compound 9) is a potent glucokinase activator, with an EC50 of 0.09 μM. Glucokinase activator 6 can be used for type 2 diabetes (T2D) research[1]. | [References]
[1] Kumari V, et al. Comparative docking assessment of glucokinase interactions with its allosteric activators. Curr Chem Genomics. 2008 Dec 30;2:76-89. DOI:10.2174/1875397300802010076 |
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