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4812-40-2

4812-40-2 Structure

4812-40-2 Structure
IdentificationBack Directory
[Name]

1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE
[CAS]

4812-40-2
[Synonyms]

MNZOH
METRONIDAZOLE-OH
Hydroxy Metronidazo
Metronidazole-hydroxy
HYDROXY METRONIDAZOLE
Metronidazole-OH MNZOH
Metronidazole Impurity H
2-(HydroxyMethyl)-5-nitro-
Metronidazole EP Impurity H
ROXYMETHYL-5-NITROIMIDAZOLE
1-(2-Hydroxyethyl)-2-hydroxymethyl-
Metronidazole-hydroxy solution,100ppm
2-hydroxymethyl-5-nitro-imidazole-1-ethano
MNZOH, Hydroxy metronidazole Solution, 100ppm
4-Hydroxy-2-methyl-5-nitro-1H-imidazole-1-ethanol
1H-IMidazole-1-ethanol, 2-(hydroxyMethyl)-5-nitro-
1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE
Metronidazole-hydroxy solution,1000ppm solution,100ppm
1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (Hydroxy
1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH
Metronidazole-OH,1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH
Hydroxy MetronidazoleQ: What is Hydroxy Metronidazole Q: What is the CAS Number of Hydroxy Metronidazole Q: What is the storage condition of Hydroxy Metronidazole Q: What are the applications of Hydroxy Metronidazole
Hydroxy Metronidazole D2Q: What is Hydroxy Metronidazole D2 Q: What is the CAS Number of Hydroxy Metronidazole D2 Q: What is the storage condition of Hydroxy Metronidazole D2 Q: What are the applications of Hydroxy Metronidazole D2
[Molecular Formula]

C6H9N3O4
[MDL Number]

MFCD01721480
[MOL File]

4812-40-2.mol
[Molecular Weight]

187.15
Chemical PropertiesBack Directory
[Melting point ]

118-121°C
[Boiling point ]

321.89°C (rough estimate)
[density ]

1.4796 (rough estimate)
[refractive index ]

1.5800 (estimate)
[storage temp. ]

-20?C Freezer
[solubility ]

DMSO (Sparingly), Methanol (Slightly)
[form ]

neat
[pka]

13.28±0.10(Predicted)
[color ]

White to Light Beige
[Major Application]

forensics and toxicology
pharmaceutical (small molecule)
[InChI]

InChI=1S/C6H9N3O4/c10-2-1-8-5(4-11)7-3-6(8)9(12)13/h3,10-11H,1-2,4H2
[InChIKey]

AEHPOYAOLCAMIU-UHFFFAOYSA-N
[SMILES]

C1(CO)N(CCO)C([N+]([O-])=O)=CN=1
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H335-H319-H315
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
[Safety Statements ]

24/25
[WGK Germany ]

3
[RTECS ]

NI5568000
[HS Code ]

29332900
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

Hydroxy metronidazole is a metabolite of metronidazole. Metronidazole belongs to the nitroimidazole class of drugs. In agricultural production, it is often used as a drug to expel parasites in animals. After being added to animal feed, metronidazole remains in eggs. Because metronidazole has a variety of toxic and side effects on the human body, especially its potential carcinogenicity and hereditary mutation effects, and metronidazole can be rapidly distributed throughout the body after entering the human body, so the residual metronidazole and its metabolites in eggs inspection is necessary.
[Chemical Properties]

Off-White Solid
[Uses]

A metabolite of Metronidazole (M338880).
[Definition]

ChEBI: Metronidazole-OH is a member of imidazoles and a C-nitro compound.
[Biological Activity]

Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Item No. 9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 μg/ml, respectively). It has been found in pork and porcine plasma.
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