| Identification | Back Directory | [Name]
Cyprodinil | [CAS]
121552-61-2 | [Synonyms]
Unix
chorus
Hsdb 7019
CGA 219417
CYPRODINIL
CYPRODYNIL
Chorus 75WG
Cyprodinil 0.1
Cyprodinil Standard
CYPRODINIL PESTANAL, 250 MG
Cyprodinil Solution, 100ppm
Cyprodinil Solution, 1000ppm
CyprodinilSolution,10mg/L,1ml
Cyprodinil Reference Material
Cyprodinil@1 mg/mL in Acetone
CyprodinilSolution,100mg/L,1ml
Cyprodinil 500mg [121552-61-2]
CyprodinilSolution,100mg/L,5x1ml
4-CYCLOPROPYL-6-METHYL-N-PHENYLPYRIMIDIN-2-AMINE
4-Cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine
2-Pyrimidinamine, 4-cyclopropyl-6-methyl-N-phenyl- | [Molecular Formula]
C14H15N3 | [MDL Number]
MFCD01632330 | [MOL File]
121552-61-2.mol | [Molecular Weight]
225.29 |
| Chemical Properties | Back Directory | [Appearance]
White crystalline solid or beige powder | [Melting point ]
75.9° | [Boiling point ]
406.0±48.0 °C(Predicted) | [density ]
1.21 g/cm3 | [vapor pressure ]
5.1 x l0-4 Pa (25 °C) | [storage temp. ]
0-6°C | [solubility ]
Chloroform: Slightly Soluble | [form ]
neat | [pka]
4.44 (base) | [Water Solubility ]
20 mg l-1 (pH 5), 13 mg l-1 (pH 7),
15 mg l-1 (pH 9) 25 °C | [color ]
White to off-white | [BRN ]
7813601 | [Henry's Law Constant]
1.2×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [Major Application]
agriculture
environmental | [InChI]
InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) | [InChIKey]
HAORKNGNJCEJBX-UHFFFAOYSA-N | [SMILES]
C1(NC2=CC=CC=C2)=NC(C)=CC(C2CC2)=N1 | [LogP]
4.000 | [EPA Substance Registry System]
2-Pyrimidinamine, 4-cyclopropyl-6-methyl-N-phenyl- (121552-61-2) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline solid or beige powder | [Chemical Properties]
White to Off-White Solid | [Uses]
Cyprodinil is a broad-spectrum fungicide of the class of pyrimidinamines. It is commonly used for protection of cereal crops and fruits against fungal infections. | [Definition]
ChEBI: A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens includi
g Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as w
ll as most aquatic organisms and earthworms, but it is not considered toxic to honeybees. | [Uses]
Agricultural fungicide. | [Agricultural Uses]
Fungicide: Cyprodinil is applied to the foliage of almonds, grapes, stone fruit crops, and pome fruit crops to control plant diseases. Target fungi for cyprodinil include scab and brown rot blossom | [Trade name]
CGA 219417® technical; CHORUS®; SWITCH®; UNIX®; VANGUARD® | [Potential Exposure]
Cyprodinil is an anilino pyrimidine
fungicide applied to the foliage of almonds, grapes, stone
fruit crops, and pome fruit crops to control plant diseases.
Target fungi for cyprodinil include scab and brown rot
blossom | [Shipping]
UN3082 Environmentally hazardous substances,
liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz-
ardous material, Technical Name Required. UN3077
Environmentally hazardous substances, solid, n.o.s., Hazard
class: 9; Labels: 9-Miscellaneous hazardous material,
Technical Name Required. | [Incompatibilities]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions) if
breathing has stopped, and CPR if heart action has stopped.
Transfer promptly to a medical facility. When this chemical
has been swallowed, get medical attention. Give large
quantities of water and induce vomiting. Do not make an
unconscious person vomit. Do not induce vomiting when
formulations containing petroleum solvents are ingested. | [Description]
Cyprodinil is a systemic, broad-spectrum fungicide. It has a moderate aqueous solubility, is unlikely to leach to groundwater and is volatile. In soils it is moderately persistent but may be persistent in water systems depending on local conditions. It is moderately toxic to mammals and there is some concern that it may bioaccumulate. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds, most aquatic organisms and earthworms. It is not considered toxic to honeybees. | [Waste Disposal]
Recycle any unused portion
of the material for its approved use or return it to the manu-
facturer or supplier. Ultimate disposal of the chemical must
consider: the material’s impact on air quality; potential
migration in soil or water; effects on animal, aquatic, and
plant life; and conformance with environmental and public
health regulations. | [Production Methods]
The production of cyprodinil involves constructing a pyrimidine ring system and attaching it to a substituted phenyl group via a propyl linker. Key intermediates include 2-cyanophenyl derivatives and aminopyrimidines, which undergo alkylation and condensation reactions under controlled conditions to yield the active compound. | [Mechanism of action]
Systemic, absorbed through foliage. Inhibits amino acid biosynthesis. | [Metabolic pathway]
After single oral administration of 14C-cyprodinil to rats,
cyprodinil is rapidly eliminated principally in the urine.
The pattern of the metabolic profile in the urine exhibits
a significant sex-related difference with respect to the
major metabolite. Males and females both produce N-4-
(hydroxyphenyl)-4-cyclopropyl-5-hydroxy-6-
methylpyrimidin-2-yl-amine. Female rats conjugate this
dihydroxy metabolite with sulfate exclusively at the 5-
hydroxypyrimidinyl moiety, while males form equal
amounts of the monosulfate and disulfate conjugates.
Ten cultures of 12 collected microorganisms produce a
monohydroxylated metabolite and the filamentous
fungus, Beauveria bassiana ATCC 7159, produces a
methoxylated glycoside of the monohydroxylated
metabolite. Dihydroxylated metabolites and a molecular
cleavage product, 4-cyclopropyl-6-methyl-2-
pyrimidinylamine, are detected in certain cultures. | [storage]
Store at -20°C | [Degradation]
Cyprodinil (1) is stable to hydrolytic degradation in pH 5-9 buffer solutions
at 25 °C with a DT50 >1 year. Cyprodinil degrades rapidly in water
when exposed to UV light (DT50 ca. 14 days) (PM). | [Pesticide Type]
Fungicide |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
|