| Identification | Back Directory | [Name]
SARPAGINE | [CAS]
482-68-8 | [Synonyms]
Raupin
Raupine
SARPAGINE
sarpagan-10,17-diol
Sarpagane-10,17-diol | [EINECS(EC#)]
207-583-2 | [Molecular Formula]
C19H22N2O2 | [MDL Number]
MFCD29078461 | [MOL File]
482-68-8.mol | [Molecular Weight]
310.39 |
| Chemical Properties | Back Directory | [Melting point ]
320°C | [alpha ]
D20 +54° (c = 0.5 in pyridine) | [Boiling point ]
450.55°C (rough estimate) | [density ]
1.1396 (rough estimate) | [refractive index ]
1.5600 (estimate) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
10.24±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
This base has been isolated from Rauwolfia serpentina and is an isomer of
Ajmalinine (q.v.). Pharmacologically it has between three and four times the
effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very
specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body
weight. The toxicity is low. | [Uses]
Sarpagine is an alkaloid that can be isolated from Colombian Rauwolfia hirsufa[1]. | [Definition]
ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17. | [References]
Bodendorf, Eder., Naturwis<., 40, 342 (1953) |
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