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484049-04-9

484049-04-9 Structure

484049-04-9 Structure
IdentificationBack Directory
[Name]

5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione
[CAS]

484049-04-9
[Synonyms]

104868
DPH >=98% (HPLC)
5-(1,3-diaryl-1H-pyrazol-4-yl)hydantoin
5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-2,4-imidazolidinedione
5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione
2,4-Imidazolidinedione, 5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-
[Molecular Formula]

C18H13FN4O2
[MDL Number]

MFCD03268950
[MOL File]

484049-04-9.mol
[Molecular Weight]

336.32
Chemical PropertiesBack Directory
[density ]

1.45
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥10mg/mL
[form ]

powder
[pka]

8.36±0.10(Predicted)
[color ]

white to tan
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

DPH may be used in c-Abl tyrosine kinase-mediated cell signaling studies.
[Biochem/physiol Actions]

DPH is a potent cell permeable c-Abl activator. DPH binds to the myristoyl binding site and leads to activation of c-Abl kinase activity. The compound stimulates the phosphorylation of c-Abl and its downstream substrate Crk.
Spectrum DetailBack Directory
[Spectrum Detail]

5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione(484049-04-9)1HNMR
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