| Identification | More | [Name]
3',4',7-Trihydroxyisoflavone | [CAS]
485-63-2 | [Synonyms]
3',4',7-TRIHYDROXYISOFLAVONE
3'-HYDROXYDAIDZEIN
7,3',4'-TRIHYDROXYISOFLAVONE
HYDROXYDAIDZEIN, 3'-
MIF-TAUTOMERASE INHIBITOR I
3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one
3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one
3-(3,4-Dihydroxyphenyl)-7-hydroxychromone | [Molecular Formula]
C15H10O5 | [MDL Number]
MFCD00143002 | [Molecular Weight]
270.24 | [MOL File]
485-63-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
280-282°C | [Boiling point ]
572.8±50.0 °C(Predicted) | [density ]
1.548±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.86±0.20(Predicted) | [color ]
Off-White | [Usage]
Inhibits ?galactosidase enzyme | [BRN ]
251800 | [Stability:]
Store in Freezer | [Cosmetics Ingredients Functions]
SKIN CONDITIONING
SKIN PROTECTING
ANTIOXIDANT | [LogP]
2.580 (est) | [CAS DataBase Reference]
485-63-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
10 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Inhibits ?galactosidase enzyme | [Uses]
Inhibits β-galactosidase enzyme. | [Definition]
ChEBI: 3',4',7-trihydroxyisoflavone is a 7-hydroxyisoflavone that is daidzein substituted by a hydroxy group at position 3'. It has a role as a metabolite, an antineoplastic agent and an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor. It is functionally related to a daidzein. | [in vivo]
In a mouse skin tumorigenesis model, 7,3',4'-Trihydroxyisoflavone strongly suppresses the incidence, multiplicity, and volume of UVB-induced mouse skin tumors. Consistent with the tumor data, 7,3',4'-Trihydroxyisoflavone clearly attenuates UVB-induced COX-2 expression in hairless mouse skin[2]. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|