| Identification | Back Directory | [Name]
t-Boc-Cystamine | [CAS]
485800-26-8 | [Synonyms]
Boc-Cystamine
t-Boc-Cystamine
tert-Butyl 2-[2-(2-aminoethyl)disulfanyl]ethylcarbamate
tert-butyl (2-((2-aminoethyl)disulfanyl)ethyl)carbamate
Carbamic acid, N-[2-[(2-aminoethyl)dithio]ethyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C9H20N2O2S2 | [MDL Number]
MFCD19443372 | [MOL File]
485800-26-8.mol | [Molecular Weight]
252.4 |
| Hazard Information | Back Directory | [Chemical Properties]
T-Boc-Cystamine is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs). | [Uses]
Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
| [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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