| Identification | More | [Name]
Cystamine dihydrochloride | [CAS]
56-17-7 | [Synonyms]
2,2'-DIAMINODIETHYL DISULFIDE DIHYDROCHLORIDE
2,2-DITHIOBIS(ETHYLAMINE)DI HCL
2,2'-DITHIOBIS(ETHYLAMINE) DIHYDROCHLORIDE
2,2'-dithiodi(ethylammonium) dichloride
BIS(2-AMINOETHYL)DISULFIDE DI HCL
BIS(2-AMINOETHYL) DISULFIDE DIHYDROCHLORIDE
CYSTAMINE DIHYDROCHLORIDE
CYSTAMINIUM DICHLORIDE
DECARBOXYCYSTINE DIHYDROCHLORIDE
OYSTAMINE DIHYDROCHLORIDE
TIMTEC-BB SBB003325
2,2’-dithiobis-ethanamindihydrochloride
2,2’-dithiobis-ethylamindihydrochloride
2-aminoethyldisulfidedihydrochloride
aed
cystaminedihcl
usafcb-34
Bis(2-aminoethyl) disulphide dihydrochloride
di(2-aminoethyl) disulphide dihydrochloride
Cystamine 2HCl | [EINECS(EC#)]
200-260-7 | [Molecular Formula]
C4H14Cl2N2S2 | [MDL Number]
MFCD00012905 | [Molecular Weight]
225.2 | [MOL File]
56-17-7.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
217-220 °C (dec.)(lit.)
| [storage temp. ]
Store below +30°C. | [solubility ]
H2O: soluble1.0g/10 mL, clear to almost clear, colorless to almost colorless (<5.5 NTU) | [form ]
Crystalline Powder, Crystals or Chunks | [color ]
White to yellow | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [biological source]
synthetic | [Water Solubility ]
soluble | [Sensitive ]
Hygroscopic | [Merck ]
14,2776 | [BRN ]
3616850 | [InChI]
InChI=1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H | [InChIKey]
YUFRRMZSSPQMOS-UHFFFAOYSA-N | [SMILES]
S(CCN)SCCN.Cl.Cl | [CAS DataBase Reference]
56-17-7(CAS DataBase Reference) | [EPA Substance Registry System]
56-17-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
KR7260000
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29309070 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral | [Safety Profile]
A poison by
subcutaneous and intraperitoneal routes.
Experimental reproductive effects. When
heated to decomposition it emits very toxic
fumes of HCl, SOx, and NOx. See also
SULFIDES. |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
hepatoprotectant, t-glutaminase inhibitor, heat shock protein promoter, caspase inhibitor | [Uses]
sulfhydryl modifying reagent and heparin antagonist | [Synthesis]
Weigh 864g of composite glue, 1620g of water, 4320g of cysteamine hydrochloride, 120 mesh powdered silica 2376g and 1620g of ammonia caseic acid, add the composite glue to water, add cysteamine hydrochloride, stir well, placed at room temperature for 2h, | [storage]
room temperature (desiccate) | [Purification Methods]
Recrystallise the salt by dissolving in EtOH containing a few drops of dry EtOH/HCl, filtering and adding dry Et2O. The solid is dried in a vacuum and stored in a dry and dark atmosphere. It has been recrystallised from EtOH (solubility: 1g in 60mL of boiling EtOH) or MeOH (plates). The free base has b 90-Purification of Biochemicals — Amino Acids and Peptides 100o/0.001mm, 106-108o/5mm and 135-136o/760mm, d 4 1.1559, n D 1.5720. [Verly & Koch Biochem J 58 663 1954, Gonick et al. J Am Chem Soc 76 4671 1954, Jackson & Block J Biol Chem 113 137 1936.] The dihydrobromide has m 238-239o (from EtOH/Et2O) [Viscontini Helv Chim Acta 36 835 1953]. [Beilstein 4 H 287, 4 IV 1578.] |
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