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486-28-2

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486-28-2 Structure

486-28-2 Structure
IdentificationBack Directory
[Name]

FRAXINOL
[CAS]

486-28-2
[Synonyms]

Fraxil
FRAXINOL
5,7-Dimethoxy-6-hydroxycoumarin
6-Hydroxy-5,7-dimethoxycoumarin
6-Hydroxy-5,7-dimethoxy-chromen-2-one
6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one
[Molecular Formula]

C11H10O5
[MDL Number]

MFCD08693526
[MOL File]

486-28-2.mol
[Molecular Weight]

222.19
Chemical PropertiesBack Directory
[Melting point ]

170-172℃
[Boiling point ]

449.7±45.0 °C(Predicted)
[density ]

1.358
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO and methanol;
[form ]

powder
[pka]

8.95±0.20(Predicted)
[color ]

White-yellowish
[Water Solubility ]

slightly soluble in water
[CAS DataBase Reference]

486-28-2
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Description]

Fraxinol is a coumarin originally isolated from Ash tree bark. It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC50s = 193 and 165 μM, respectively). Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.
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