ChemicalBook--->CAS DataBase List--->497259-23-1

497259-23-1

497259-23-1 Structure

497259-23-1 Structure
IdentificationBack Directory
[Name]

TPPB
[CAS]

497259-23-1
[Synonyms]

TPPB
CS-2585
α-AMyloid Precursor Protein Modulator
Α-AMYLOID PRECURSOR PROTEIN MODULATOR
alpha-AMyloid Precursor Protein Modulator
α-Amyloid Precursor Protein Modulator, >=98%
TPPB/ α-Amyloid Precursor Protein Modulator
(2E,4E)-N-[(2S,5R)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1-benzazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide
(2E,4E)-N-((2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydrobenzo[e][1,4]diazocin-8-yl)-5-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
2,4-Pentadienamide, N-[(2S,5S)-1,2,3,4,5,6-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-
[EINECS(EC#)]

230-025-4
[Molecular Formula]

C27H30F3N3O3
[MDL Number]

MFCD09037558
[MOL File]

497259-23-1.mol
[Molecular Weight]

501.541
Chemical PropertiesBack Directory
[Boiling point ]

728.8±60.0 °C(Predicted)
[density ]

1.229
[storage temp. ]

Store at -20°C
[solubility ]

25.08mg/mL in DMSO
[form ]

Solid
[pka]

12.76±0.60(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

TPPB is a protein kinase C (PKC) activator.
[Biological Activity]

Cell permeable: yes''Primary Target
PKC''Product does not compete with ATP.''Reversible: no''Target Ki: 11.9 nM for activating PKCα
[storage]

Store at -20°C
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