Identification | Back Directory | [Name]
Benzyl-PEG2-Tos | [CAS]
4981-83-3 | [Synonyms]
Benzyl-PEG2-Tos Benzyl-PEG1-Tos 2-(Benzyloxy)ethanol tosylate 2-(Benzyloxy)ethyl p-toluenesulfonate 2-benzyloxy-1-(p-toluenesulfonyloxy)ethane 2-(Benzyloxy)ethyl 4-methylbenzenesulfonate Ethanol, 2-(phenylmethoxy)-, 4-methylbenzenesulfonate | [Molecular Formula]
C16H18O4S | [MDL Number]
MFCD00027610 | [MOL File]
4981-83-3.mol | [Molecular Weight]
306.38 |
Hazard Information | Back Directory | [Description]
Benzyl-PEG2-Tos is a PEG linker with an acid labile, benzyl protecting group. The tosyl group is a good leaving group. The hydrophilic PEG linker increases the water solubility of the compound in aqueous solutions. | [Uses]
Benzyl-PEG1-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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