| Identification | Back Directory | [Name]
4-Chlorophenylglyoxal hydrate | [CAS]
4996-21-8 | [Synonyms]
Zinc01703019
4-CHLOROPHENYLGLYOXAL HYDRATE
4-Chlorophenylglyoxal hydrate 95%
4-CHLOROPHENYLGLYOXAL HYDRATE, 95+%
Ethanone, 1-(4-chlorophenyl)-2,2-dihydroxy- | [Molecular Formula]
C8H7ClO3 | [MDL Number]
MFCD08272327 | [MOL File]
4996-21-8.mol | [Molecular Weight]
186.59 |
| Chemical Properties | Back Directory | [Boiling point ]
319.0±27.0 °C(Predicted) | [density ]
1.454±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [pka]
10.42±0.41(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
The general procedure for the synthesis of 4-chlorophenyl acetaldehyde hydrate from α-bromo-4-chloroacetophenone was as follows: 4'-chloro-2-bromoacetophenone (25.0 g, 107 mmol), water (1.92 mL, 107 mmol), and 47% hydrobromic acid (0.20 mL) were dissolved in dimethylsulfoxide (160 mL), and the reaction was stirred for 5 hr at 80 °C. Upon completion of the reaction, the reaction mixture was poured into water and the precipitate precipitated was filtered, washed with diethyl ether and dried to give 4-chloro-2,2-dihydroxyacetylbenzene (14.0 g, yield not indicated). The product was characterized by 1H NMR (300 MHz, CDCl3) with chemical shifts of δ 5.92 (1H, s), 7.45-7.52 (2H, m), 8.05-8.20 (2H, m). | [References]
[1] Patent: WO2004/85408, 2004, A1. Location in patent: Page 276 |
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