ChemicalBook--->CAS DataBase List--->503-87-7

503-87-7

503-87-7 Structure

503-87-7 Structure
IdentificationMore
[Name]

2-Thiohydantoin
[CAS]

503-87-7
[Synonyms]

2-THIOHYDANTION
2-THIOHYDANTOIN
2-Thioguidanthion
2-thio-hydantoi
2-thioxo-4-imidazolidinon
2-Thioxo-4-imidazolidinone
2-Thioxo-4-imidazolinone
4-Imidazolidinone,2-thioxo-
Glycine thiohydantoin
Hydantoin, 2-thio-
Thiohydantoin
USAF be-25
usafbe-25
2-THIOHYTANTOIN
2-Thiohydantoine
2-THIOHYDANTOIN 97+%
4-Oxo-2-imidazolidinethione
Glycolylthiourea
[EINECS(EC#)]

207-977-4
[Molecular Formula]

C3H4N2OS
[MDL Number]

MFCD00005277
[Molecular Weight]

116.14
[MOL File]

503-87-7.mol
Chemical PropertiesBack Directory
[Appearance]

BROWN CRYSTALLINE POWDER
[Melting point ]

229-231 °C (dec.)(lit.)
[density ]

1.346 (estimate)
[vapor density ]

4 (vs air)
[refractive index ]

1.6550 (estimate)
[storage temp. ]

Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Crystalline Powder
[pka]

8.50±0.10(Predicted)
[color ]

White
[InChI]

1S/C3H4N2OS/c6-2-1-4-3(7)5-2/h1H2,(H2,4,5,6,7)
[InChIKey]

UGWULZWUXSCWPX-UHFFFAOYSA-N
[SMILES]

O=C1CNC(=S)N1
[CAS DataBase Reference]

503-87-7(CAS DataBase Reference)
[NIST Chemistry Reference]

4-Imidazolidinone, 2-thioxo-(503-87-7)
[EPA Substance Registry System]

503-87-7(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R22:Harmful if swallowed.
[Safety Statements ]

S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

MU4200000
[TSCA ]

Yes
[HS Code ]

2934999090
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Hazard InformationBack Directory
[Chemical Properties]

BROWN CRYSTALLINE POWDER
[Uses]

Reactant for synthesis of:
  • Drugs with antidiabetic activity
  • Barbituric acid and thiohydantoin derivatives with antimicrobial activity
  • Possible anticancer agents
  • Fibroblast growth factor receptor 1 kinase inhibitors
  • HIV-1 integrase inhibitors

Reactant for persilylation
[Uses]

2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
[Uses]

Reactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

2-Thiohydantoin(503-87-7)MS
2-Thiohydantoin(503-87-7)1HNMR
2-Thiohydantoin(503-87-7)IR1
2-Thiohydantoin(503-87-7)IR2
2-Thiohydantoin(503-87-7)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

2-Thiohydantoin, 99%(503-87-7)
[Sigma Aldrich]

503-87-7(sigmaaldrich)
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