| Identification | Back Directory | [Name]
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | [CAS]
503615-07-4 | [Synonyms]
X5909
TECO-012
Apixaban Impurity 81
Apixaban interMediate
Intermediates of apixaban
Apixaban Impurity 11
ethyl
Apixaban Stage-II impurity
ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-te...
ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-ca
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 6-(4-aMinophenyl)-4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-, ethyl ester
Apixaban Impurity 4
ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-
tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | [EINECS(EC#)]
948-272-8 | [Molecular Formula]
C22H22N4O4 | [MDL Number]
MFCD18251628 | [MOL File]
503615-07-4.mol | [Molecular Weight]
406.434 |
| Chemical Properties | Back Directory | [Boiling point ]
651.6±55.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), DMF (Slightly) | [form ]
Solid | [pka]
4.66±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C22H22N4O4/c1-3-30-22(28)19-18-12-13-25(15-6-4-14(23)5-7-15)21(27)20(18)26(24-19)16-8-10-17(29-2)11-9-16/h4-11H,3,12-13,23H2,1-2H3 | [InChIKey]
UVAQGQOGOJLALA-UHFFFAOYSA-N | [SMILES]
C1(=O)N(C2=CC=C(N)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2 |
| Hazard Information | Back Directory | [Uses]
Ethyl 6-?(4-?Aminophenyl)?-?1-?(4-methoxyphenyl)?-?7-?oxo-?4,?5,?6,?7-?tetrahydro-?1H-?pyrazolo[3,?4-?c]?pyridine-?3-?carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. |
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