| Identification | Back Directory | [Name]
Vasicil | [CAS]
5081-51-6 | [Synonyms]
Vasicil
6-Hydroxypeganine
6-Hydroxyvasicine
(+)-6-Hydroxypeganine
Pyrrolo(2,1-b)quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (R)-
Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3S)- | [Molecular Formula]
C11H12N2O2 | [MDL Number]
MFCD31618849 | [MOL File]
5081-51-6.mol | [Molecular Weight]
204.23 |
| Chemical Properties | Back Directory | [Melting point ]
260 °C | [Boiling point ]
465.0±55.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.89±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2]. | [Definition]
ChEBI: Vasicinol is a member of quinazolines. | [References]
[1] Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108(3):965-72. DOI:10.1016/j.foodchem.2007.12.002
[2] Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26(22):6971. DOI:10.3390/molecules26226971 |
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| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
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| Telephone: |
+86-29-87569266 +86-17392581500 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-220/ |
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