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510-64-5

510-64-5 Structure

510-64-5 Structure
IdentificationMore
[Name]

19-HYDROXY-4-ANDROSTENE-3,17-DIONE
[CAS]

510-64-5
[Synonyms]

19-HYDROXY-4-ANDROSTEN-3,17-DIONE
19-HYDROXY-4-ANDROSTENE-3,17-DIONE
19-HYDROXYANDROSTENDIONE
19-HYDROXYANDROSTENEDIONE
4-ANDROSTEN-19-OL-3,17-DIONE
4-ANDROSTENE-3,17-DIONE-19-0L
4-ANDROSTENE-3,17-DIONE-19-OL
Androst-4-ene-3,17-dione, 19-hydroxy-
19-hydroxyandrost-4-ene-3,17-dione
Androst-4-en-19-ol-3,17-dione
Androst-4-ene-3,17-dione-19-ol
NSC 7423
19-HUDROXYANDROST-4-ENE-3,17-DIONE
19-Hydroxyandrost-4-ene-3,17-d
(8S,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
19-hydroxy-4-androstene-3,17-dione 19-hydroxy-4-androsten-3,17-dione19-Hydroxyandrost-4-ene-3,17-dione
NSC 74233
19-Hydroxy-4-androstene-3,17-dione, 4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol
4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol
[EINECS(EC#)]

208-116-5
[Molecular Formula]

C19H26O3
[MDL Number]

MFCD00003616
[Molecular Weight]

302.41
[MOL File]

510-64-5.mol
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

168-169 °C(lit.)
[Boiling point ]

485.4±45.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Store in freezer, under -20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

14.90±0.10(Predicted)
[color ]

Off-White to Pale Yellow
[Optical Rotation]

[α]/D +190±5°, c = 1 in chloroform
[Usage]

A novel substituted estrogen as aromatase inhibitor
[BRN ]

2567249
[CAS DataBase Reference]

510-64-5(CAS DataBase Reference)
[NIST Chemistry Reference]

19-Hydroxyandrost-4-ene-3,17-dione(510-64-5)
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Warning
[Hazard statements ]

H361
[Precautionary statements ]

P281
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[HS Code ]

29372900
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Isopropyl acetate
[Preparation Products]

Norethindrone-->3,3-Dimethoxyestr-5(10)-ene-17-one
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.
[Uses]

A novel substituted estrogen as aromatase inhibitor
[Definition]

ChEBI: 19-hydroxyandrost-4-ene-3,17-dione is a 19-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a mouse metabolite.
[Purification Methods]

Recrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.]
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

510-64-5(sigmaaldrich)
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