| Identification | Back Directory | [Name]
ACTIN FROM RABBIT MUSCLE | [CAS]
51005-14-2 | [Synonyms]
Rabbit Muscle
β-actin antibody
Actin from rabbit muscle >=85% (SDS-PAGE), lyophilized powder | [EINECS(EC#)]
297-218-3 | [MDL Number]
MFCD00130338 |
| Hazard Information | Back Directory | [Description]
Actin, with a molecular weight of 42 kDa, is a globular, multifunctional protein that forms microfilaments and is present in virtually all eukaryotic cells. In mammals, at least six actin isoforms are encoded by distinct genes, categorized into three classes (α, β, and γ) based on their isoelectric points. Generally, α-actins are found in muscle tissues (α-skeletal, α-aortic smooth, α-cardiac), while β and γ isoforms predominate in non-muscle cells (β-cytoplasmic, γ1-cytoplasmic, γ2-intestinal smooth). | [Uses]
Actin from bovine muscle has been used as an internal standard and positive control during western blotting. | [Uses]
Actin from rabbit muscle has been used:
- to study its protective role on rabbit muscle lactate dehydrogenase from ascorbate inhibition
- as standard in SDS gel?and immunoblotting
- in the protein pin array assays
| [Uses]
Used in cell transport studies, and inhibits deoxyribonuclease I | [General Description]
Actin is the abundant protein found in many cells which accounts for 10% or more of total protein. Most of the eukaryotic cells shows the presence of actin protein. Outer and inner domains are the two important domains of actin. | [Biochem/physiol Actions]
Actin is involved in a wide variety of cellular processes like cell migration, phagocytosis, cell polarity and shape. It associates with myosin and aids in muscle contraction. The protein acts as a building block of microfilaments. |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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