| Identification | Back Directory | [Name]
(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL | [CAS]
511-96-6 | [Synonyms]
DIGIN
Digine
GITOGENIN
NSC 147752
2alpha-Hydroxytigogenin
Gitogenin
NSC 147752
(2a,3b,5a,25R)-Spirostan-2,3-diol
(25R)-2α,3β-Dihydroxy-5α-spirostan
(25R)-2α,3β-Dihydroxy-5α-spirostane
Spirostan-2,3-diol, (2α,3β,5α,25R)-
(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
(2alpha,3β,5alpha,25R)-Spirostan-2,3-diol
GITOGENIN; (2A,3B,5A,25R)-SPIROSTAN-2,3-DIOL
(2alpha,3beta,5alpha,25R)-Spirostan-2,3-diol | [Molecular Formula]
C27H44O4 | [MDL Number]
MFCD00273328 | [MOL File]
511-96-6.mol | [Molecular Weight]
432.64 |
| Chemical Properties | Back Directory | [Melting point ]
272-273℃ | [alpha ]
D20 -75° (c = 1.02 in CHCl3) | [Boiling point ]
466.26°C (rough estimate) | [density ]
1.16 | [refractive index ]
1.4840 (estimate) | [solubility ]
Chloroform: 30 mg/ml | [form ]
A solid | [pka]
14.62±0.70(Predicted) | [color ]
White to off-white | [InChIKey]
FWCXELAAYFYCSR-RYKNUXCGSA-N | [SMILES]
O[C@H]1[C@H](O)C[C@@](CC[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])C[C@@]5([H])[C@]4([H])[C@H](C)[C@]6(OC[C@H](C)CC6)O5)([H])[C@]3(C)C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus, Saposhnikovia divaricata, Fenugreek root, Tribulus terrestris root, and Giant fish maw flower. | [Uses]
Gitogenin is isolated from a methanolic extract of the whole plant of Tribulus longipetalus which exhibits inhibitory activities against α-glucosidase, lipoxygenase, acetylcholinesterase and butyrylcholinesterase. | [Definition]
ChEBI: Gitogenin is a triterpenoid. | [in vivo]
Stimulation of growth hormone release is investigated on rat pituitary cells in vitro. Gitogenin (20 μg/mL) shows rat growth-hormone (rGH) release stimulating activities (26.1 ng/mL)[3]. |
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