| Identification | Back Directory | [Name]
RUBROPUNCTATIN | [CAS]
514-67-0 | [Synonyms]
RUBROPUNCTATIN
Rubropuncatatin
(9aR)-3-hexanoyl-9a-methyl-6-[(E)-prop-1-enyl]furo[3,2-g]isochromene-2,9-dione
(R-(E))-9A-Methyl-3-(1-oxohexyl)-6-(1-propenyl)-2H-furo(3,2-G)(2)benzopyran-2,9(9ah)-dione
(R)-9a-Methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(9aH)-dione
2H-Furo(3,2-G)(2)benzopyran-2,9(9ah)-dione, 9A-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, (R-(E))-
2H-Furo[3,2-g][2]benzopyran-2,9(9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (9aR)- | [Molecular Formula]
C21H22O5 | [MDL Number]
MFCD34470836 | [MOL File]
514-67-0.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Melting point ]
156.5-157.0 °C (decomp)(Solv: ethyl ether (60-29-7)) | [Boiling point ]
638.8±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
Yellow to orange | [InChI]
InChI=1S/C21H22O5/c1-4-6-7-9-17(22)18-16-11-13-10-14(8-5-2)25-12-15(13)19(23)21(16,3)26-20(18)24/h5,8,10-12H,4,6-7,9H2,1-3H3/b8-5+/t21-/m1/s1 | [InChIKey]
SULYDLFVUNXAMP-WKOQKXSESA-N | [SMILES]
C1(/C=C/C)OC=C2C(=O)[C@]3(C)OC(=O)C(C(=O)CCCCC)=C3C=C2C=1 |
| Hazard Information | Back Directory | [Uses]
Rubropunctatin is used in preparation Method for separating and purifying Rubropunctatin in monascus polished glutinous rice. | [in vivo]
Rubropunctatin (8-32 mg/kg; i.v. for 5 times) has anti-tumor effect mice[1].
Rubropunctamine inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, with an ID50 of 0.11 mg/ear[3]. | Animal Model: | Male nude mice (5 weeks) are inoculated with BGC-823 cells[1] | | Dosage: | 8, 32 mg/kg | | Administration: | I.v. five times (day 1st, 4th, 7th, 10th, and 13th) | | Result: | Diminished the tumor volume by 11.1% (8 mg/kg) and 24.2% (32 mg/kg).
Reduced the tumor weight by 23.5% (8 mg/kg) and 37.7% (32 mg/kg).
No significant difference was observed on the body weight.
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BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
Novachemistry
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44-20819178-90 02081917890 |
| Website: |
https://www.novachemistry.com/ |
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