Identification | Back Directory | [Name]
beta, beta-dimethylacrylshikonin | [CAS]
5162-01-6 | [Synonyms]
Arnebin 1 Arnebin i (Rac)-Arnebin 1 Dimethylacrylalkannin, β,β- Alkannin beta,beta-dimethylacrylate Crotonic acid, 3-methyl-, ester with 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone 2-Butenoic acid, 3-methyl-, 1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-pentenyl ester 2-Butenoic acid, 3-methyl-, 1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester | [Molecular Formula]
C21H22O6 | [MDL Number]
MFCD11042253 | [MOL File]
5162-01-6.mol | [Molecular Weight]
370.4 |
Hazard Information | Back Directory | [Uses]
(Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin) is the racemate of β,β-Dimethylacrylalkannin and/or β,β-Dimethylacrylshikonin. β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin are napthoquinones isolated from Arnebia nobilis. β,β-Dimethylacrylshikonin has anti-tumor activity[1]. | [References]
[1] Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36(3):685-97. DOI:10.3892/ijmm.2015.2292 |
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