| Identification | More | [Name]
Ketoleucine calcium salt dihydrate | [CAS]
51828-95-6 | [Synonyms]
2-KETOLEUCINE CALCIUM SALT 4-METHYL-2-OXOVALERIC ACID CALCIUM 4-METHYL-2-OXOVALERIC ACID CALCIUM SALT 4-METHYL-2-OXOVALERIC ACID CALCIUM SALT HYDRATE ALPHA-KETOLEUCINE CALCIUM SALT CALCIUM 2-KETO-4-METHYLVALERATE HYDRATE CALCIUM-4-METHYL-2-OXO-VALERATE CALCIUM 4-METHYL-2-OXOVALERATE HYDRATE CALCIUM ALPHA-KETOISOCAPROATE KETO-ISO-CAPROATE CALCIUM SALT KETO LEUCINE CALIUM SALT 4-methyl-2-oxovaleric acid calcium salt dihydr. 2-Ketoisocaproic acid calcium salt Ketoleucine calcium salt Calcium Ketoisocaproate 4-METHYL-2-OXOVALERIC ACID CALCIUM(KETO LEUCINE CALIUM SALT) A-CALCIUM KETOISOCAPROATE a-Ketoleucine Calcium Calcium2-keto-4-methylvalerate KETO-ISO-CAPROATECALCIUMSALT,POWDER | [EINECS(EC#)]
257-457-6 | [Molecular Formula]
C12H18CaO6 | [MDL Number]
MFCD00004163 | [Molecular Weight]
298.35 | [MOL File]
51828-95-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Slightly), Water (Very Slightly, Sonicated) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C6H10O3.Ca.2H/c1-4(2)3-5(7)6(8)9;;;/h4H,3H2,1-2H3,(H,8,9);;; | [InChIKey]
NQKUPRIQLTUMTG-UHFFFAOYSA-N | [SMILES]
C(=O)(C(=O)O)CC(C)C.[Ca] | [CAS DataBase Reference]
51828-95-6(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
Calcium 2-keto-4-methylvalerate ketoacid that can be used as a phosphate binder alternative for patients on peritoneal dialysis, and can be used as a supplement for very low protein diets to maintain nutritional status of patients of chronic kidney disease until arteriovenous fistula made or training for peritoneal dialysis given. |
| Hazard Information | Back Directory | [Pharmaceutical Applications]
Ketoleucine calcium salt dihydrate is the main ingredient of compound α-ketoacid tablets. Compound α-ketoacid tablets are used for the treatment of uremia, providing essential amino acids for patients with kidney disease and minimizing the intake of amino nitrogen. Keto or hydroxyamino acids do not contain amino groups themselves, and use the nitrogen of non-essential amino acids to convert them into amino acids, thereby reducing urea synthesis and reducing the accumulation of uremic toxic products. |
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