| Identification | More | [Name]
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL | [CAS]
5197-62-6 | [Synonyms]
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
2-(2-CHLOROETHOXY)ETHOXYETHANOL
TRIETHYLENE GLYCOL MONOCHLOROHYDRIN
Triethylene glycol monochloride
Chloroethoxyethoxy]ethanol
CEEE
2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL, 96+%
8-Chloro-3,6-dioxaoctane-1-ol
Diethylene glycol mono(2-chloroethyl) ether | [EINECS(EC#)]
225-984-0 | [Molecular Formula]
C6H13ClO3 | [MDL Number]
MFCD00002874 | [Molecular Weight]
168.62 | [MOL File]
5197-62-6.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Boiling point ]
117-120 °C5 mm Hg(lit.)
| [density ]
1.16 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.458(lit.)
| [Fp ]
225 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly) | [form ]
Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Clear slightly yellow | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [BRN ]
1739194 | [InChI]
InChI=1S/C6H13ClO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2 | [InChIKey]
KECMLGZOQMJIBM-UHFFFAOYSA-N | [SMILES]
C(O)COCCOCCCl | [CAS DataBase Reference]
5197-62-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [REACH Registrations]
Active | [HS Code ]
29094990 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
colourless liquid | [Uses]
2-[2-(2-Chloroethoxy)ethoxy]ethanol is used in the preparation of ethylene glycol based amino acids. 2-[2-(2-Chloroethoxy)ethoxy]ethanol is also used in the preparation of polymers for direct and amplified DNA detection. | [Synthesis]
The reaction material in the three-necked flask was cooled to 45-50°C and 0.7 g of boron trifluoride diethyl ether compound was added as catalyst. Subsequently, 46.2 g (1.05 mol) of ethylene oxide was slowly added under stirring conditions, and the addition rate was controlled to maintain the reaction temperature at 45-55°C, using a temperature-controlled water bath for temperature adjustment if necessary. After the addition, the reaction was continued with stirring for 0.5 h to ensure complete reaction. Upon completion of the reaction, the reaction was heated and distilled under reduced pressure to collect the middle fraction at 115-123°C (vacuum 10 mmHg) to obtain a colorless transparent liquid. Further vacuum distillation was carried out under reduced pressure to collect the middle fraction at 118-121 °C (vacuum 10 mmHg) to give 123.6 g of colorless transparent liquid with 97.7% purity in the gas phase and 73.3% overall yield. | [References]
[1] Patent: CN104003850, 2016, B. Location in patent: Paragraph 0039; 0040 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
|