| Identification | Back Directory | [Name]
Tricin | [CAS]
520-32-1 | [Synonyms]
TRICIN
Tricinc
TRICIN(P)
Phelipeone
Nsc 294579
3',5'-di-O-methyltricetin
Tricetin 3',5'-dimethyl ether
4',5,7-Trihydroxy-3',5'-dimethoxyflavone
5,7,4'-Trihydroxy-3',5'-dimethoxyflavone
3',5'-DIMETHOXY-4',5,7-TRIHYDROXYFLAVONE
5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)
5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromen-4-one
5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-chromen-4-one
5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxy-3,5-diMethoxyphenyl)-
5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-5,6-dihydro-4H-chromen-4-one | [Molecular Formula]
C17H14O7 | [MDL Number]
MFCD00210580 | [MOL File]
520-32-1.mol | [Molecular Weight]
330.29 |
| Questions And Answer | Back Directory | [Preparation]
A novel method for synthesizing Tricin. Phloroglucinol (2) and chloroacetonitrile were condensed in hydrochloric acid/ethyl acetate in the presence of zinc chloride to give 2-(2-chloro-1-iminoethyl)benzene-1,3,5-triol (3), which was then hydrolyzed directly in dilute hydrochloric acid without purification to give 2-chloro-1-(2,4,6-trihydroxyphenyl)ethyl ketone (4). The target compound was then cyclized with eugenol under ultrasonic treatment and in the presence of the phase-transfer catalyst tetrabutylammonium bromide (TBAB). This process uses inexpensive and readily available raw materials, has mild reaction conditions, is convenient to operate, and is green and efficient, with a total yield of 74.1%. |
| Chemical Properties | Back Directory | [Melting point ]
289～291℃ | [Boiling point ]
598.5±50.0 °C(Predicted) | [density ]
1.483±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Dichloromethane (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
6.48±0.40(Predicted) | [color ]
Yellow to Dark Yellow | [Major Application]
food and beverages | [Cosmetics Ingredients Functions]
SKIN PROTECTING
SKIN CONDITIONING | [InChI]
InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)17(14)21)12-7-11(20)16-10(19)5-9(18)6-13(16)24-12/h3-7,18-19,21H,1-2H3 | [InChIKey]
HRGUSFBJBOKSML-UHFFFAOYSA-N | [SMILES]
C1(C2=CC(OC)=C(O)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the whole herb of Medicago sativa. | [Uses]
Tricin is a type of flavanoid studied for its immunomodulatory effects. | [Definition]
ChEBI: The 3',5'-di-O-methyl ether of tricetin. Known commonly as tricin, it is a constituent of rice bran and has been found to potently inhibit colon cancer cell growth. | [in vivo]
Tricin (50-250 ppm diet; 15 weeks) significantly lowers the numbers of adenocarcinomas and total tumors in mice[5]. | [target]
TLR | p38MAPK | JNK | NF-kB | Phospholipase (e.g. PLA) | Tyrosinase | COX | JAK | STAT | Antifection | [storage]
4°C, protect from light |
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| Company Name: |
cjbscvictory Gold
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
| Company Name: |
Shanghai Ennopharm Co., Ltd.
|
| Telephone: |
+86 (21) 6435-5022 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList13640/0_EN.htm |
|