| Identification | Back Directory | [Name]
asebogenin | [CAS]
520-42-3 | [Synonyms]
asebogenin
4'-O-Methylphloretin
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone
1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)- | [Molecular Formula]
C16H16O5 | [MDL Number]
MFCD00017397 | [MOL File]
520-42-3.mol | [Molecular Weight]
288.3 |
| Hazard Information | Back Directory | [Uses]
Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2]. | [Definition]
ChEBI: A member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin. | [References]
[1] 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. DOI:10.1046/j.1365-3156.1999.00456.x
[2] Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. DOI:10.1111/bph.15964 |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|