| Identification | Back Directory | [Name]
YOHIMBINIC ACID MONOHYDRATE | [CAS]
522-87-2 | [Synonyms]
Yohimbic
YOHIMBIC ACID
yohimbine acid
yohimbinic acid
YOHIMBIC ACID(RG)
YOHIMBIC ACID HYDRATE
YOHIMBIC ACID MONOHYDRATE
YOHIMBINIC ACID MONOHYDRATE
17α-Hydroxyyohimban-16α-carboxylic acid
Yohimban-16-carboxylic acid, 17-hydroxy-, (16α,17α)- | [EINECS(EC#)]
208-337-7 | [Molecular Formula]
C20H24N2O3 | [MDL Number]
MFCD00167087 | [MOL File]
522-87-2.mol | [Molecular Weight]
340.42 |
| Chemical Properties | Back Directory | [Melting point ]
267-268 °C (dec.)(lit.)
| [Boiling point ]
600.0±50.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.19±0.40(Predicted) | [color ]
White to off-white | [LogP]
1.940 (est) |
| Hazard Information | Back Directory | [Uses]
Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action. Yohimbic acid also can be used for the research of osteoarthritis (OA)[1][2][3]. | [Definition]
ChEBI: Yohimbic acid is a yohimban alkaloid. It is functionally related to a 17alpha-yohimbol. | [References]
[1] Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20(2): 1716-1724. DOI:10.3892/mmr.2019.10389
[2] HAMET R. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. PMID:14896545
[3] HAMET R. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. PMID:13854468 |
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