| Identification | More | [Name]
H-PHE-NH2 | [CAS]
5241-58-7 | [Synonyms]
H-L-PHE-NH2
H-PHE-NH2
L-PHENYLALANINAMIDE
L-PHENYLALANINE AMIDE
PHENYLALANINE-NH2
L-phenylalaninamide free base
H-Phe-Nh
2-Amino-3-phenylpropanamide
α-Aminobenzenepropionamide | [Molecular Formula]
C9H12N2O | [MDL Number]
MFCD00038146 | [Molecular Weight]
164.2 | [MOL File]
5241-58-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
93-95°C | [Boiling point ]
356.9±35.0 °C(Predicted) | [density ]
1.143±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
15.85±0.50(Predicted) | [color ]
White | [Optical Rotation]
Consistent with structure | [BRN ]
6270941 | [Major Application]
detection | [InChI]
1S/C9H12N2O/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H2,11,12)/t8-/m0/s1 | [InChIKey]
OBSIQMZKFXFYLV-QMMMGPOBSA-N | [SMILES]
N[C@@H](Cc1ccccc1)C(N)=O | [CAS DataBase Reference]
5241-58-7(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Protected amino acid | [Definition]
ChEBI: An amino acid amide derived from L-phenylalanine. | [Biological Activity]
L-Phenylalaninamide is a chiral selector. | [Synthesis]
General procedure for the synthesis of (S)-2-amino-3-phenylpropionamide from L-phenylalanine methyl ester hydrochloride: intermediate 1 (L-phenylalanine methyl ester hydrochloride) was dissolved in 20% aqueous ammonia solution and the reaction was stirred for 20 hours at room temperature. Upon completion of the reaction, 50 mL of ethyl acetate was added to the reaction mixture and three extraction operations were performed. All organic phases were combined and the solvent was removed by rotary evaporator to afford Intermediate 2 ((S)-2-amino-3-phenylpropionamide) as a white solid in 2.5 g yield, 76%. | [References]
[1] Helvetica Chimica Acta, 2004, vol. 87, # 5, p. 1077 - 1089
[2] Organic and Biomolecular Chemistry, 2012, vol. 10, # 30, p. 6074 - 6086
[3] Chemistry - An Asian Journal, 2011, vol. 6, # 6, p. 1321 - 1324
[4] Bulletin de la Societe Chimique de France, 1989, # 5, p. 673 - 676
[5] Patent: CN108610292, 2018, A. Location in patent: Paragraph 0041; 0051; 0052 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
AF Biochem Co., Ltd.
|
| Telephone: |
+86-028-60911900 13540204019 |
| Website: |
www.afbiochem.com |
|