| Identification | More | [Name]
Tryptophol | [CAS]
526-55-6 | [Synonyms]
2-(1H-INDOL-3-YL)ETHAN-1-OL
2-(1H-INDOL-3-YL)-ETHANOL
2-(3-INDOLE)ETHANOL
3-(2-HYDROXYETHYL)INDOLE
3-(BETA-HYDROXYETHYL)INDOLE
3-INDOLEETHANOL
B-3-INDOLEETHANOL
B-3-INDOLYLETHANOL
BETA-3-INDOLYLETHANOL
INDOLE-3-ETHANOL
RARECHEM AH BS 0132
TIMTEC-BB SBB003950
TRYPTOPHOL
'TRYPTOPHOL'
TRYPTOTHOL
1H-Indole-3-ethanol
2-(3-Indolylethanol
3-indolyl-ethano
3-Indolylethanol
beta-(3-Indole)ethanol | [EINECS(EC#)]
208-393-2 | [Molecular Formula]
C10H11NO | [MDL Number]
MFCD00005659 | [Molecular Weight]
161.2 | [MOL File]
526-55-6.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to brown crystalline mass, crystals, | [Melting point ]
56-59 °C(lit.)
| [Boiling point ]
174 °C (2.02527 mmHg)
| [density ]
1.0840 (rough estimate) | [refractive index ]
1.5200 (estimate) | [Fp ]
255 °C
| [storage temp. ]
2-8°C
| [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
Crystalline Mass, Crystals, Flakes or Powder | [pka]
15.16±0.10(Predicted) | [color ]
Off-white to brown | [Water Solubility ]
10 g/L (20 ºC) | [Merck ]
14,9798 | [BRN ]
125553 | [InChIKey]
MBBOMCVGYCRMEA-UHFFFAOYSA-N | [LogP]
1.280 (est) | [CAS DataBase Reference]
526-55-6(CAS DataBase Reference) | [NIST Chemistry Reference]
1H-indole-3-ethanol(526-55-6) | [EPA Substance Registry System]
526-55-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
KL3685000
| [F ]
8 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29339990 | [Toxicity]
LD50 intraperitoneal in mouse: 351mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to brown crystalline mass, crystals, | [Uses]
Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation. | [Definition]
ChEBI: An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. | [Synthesis Reference(s)]
Canadian Journal of Chemistry, 42, p. 485, 1964 DOI: 10.1139/v64-070 | [storage]
Store at -20°C | [Purification Methods]
Crystallise it from diethyl ether/pet ether, *C6H6, *C6H6/pet ether. The picrate has m 100-101o (from *C6H6). [Beilstein 21 I 218, 21 II 49, 21 III/IV 788, 21/3 V 61.] |
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