| Identification | More | [Name]
1,2,3,4-Tetrahydro-1-naphthol | [CAS]
529-33-9 | [Synonyms]
1,2,3,4-TETRAHYDRO-1-NAPHTHOL
1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL
1-HYDROXYTETRALIN
1-TETRALOL
AC-ALPHA-TETRALOL
(+/-)-ALPHA-TETRALOL
ALPHA-TETRALOL
A-TETRALOL
1,2,3,4-tetrahydro-1-naphthaleno
1,2,3,4-Tetrahydro-1-naphthalenol
1,2,3,4-tetrahydro-1-naphtho
1,2,3,4-tetrahydro-1-napthol
1,2,3,4-Tetrahydro-alpha-naphthol
1-Naphthol, 1,2,3,4-tetrahydro-
Tetrahydro-1-naphthol
Tetralin-1-ol
1,2,3,4-Tetrahydro-a-naphthol
(1R)-1,2,3,4-Tetrahydro-1-naphthol
(1R)-Tetralin-1-ol
(R)-1-Hydroxy-1,2,3,4-tetrahydronaphthalene | [EINECS(EC#)]
208-459-0 | [Molecular Formula]
C10H12O | [MDL Number]
MFCD00001739 | [Molecular Weight]
148.2 | [MOL File]
529-33-9.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colourless to slightly brown viscous liquid | [Melting point ]
28-32 °C
| [Boiling point ]
102-104 °C2 mm Hg(lit.)
| [density ]
1.09 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.564(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
5.09g/l | [form ]
powder to lump to clear liquid | [pka]
14.33±0.20(Predicted) | [color ]
White or Colorless to Light yellow | [Specific Gravity]
1.090 | [BRN ]
2046227 | [Cosmetics Ingredients Functions]
PERFUMING | [InChI]
1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10-11H,3,5,7H2 | [InChIKey]
JAAJQSRLGAYGKZ-UHFFFAOYSA-N | [SMILES]
OC1CCCc2ccccc12 | [LogP]
1.980 | [CAS DataBase Reference]
529-33-9(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Naphthalenol, 1,2,3,4-tetrahydro-(529-33-9) | [EPA Substance Registry System]
529-33-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
QL5075000
| [TSCA ]
TSCA listed | [HS Code ]
29062900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2,3,4-Tetrahydronaphthalene-->[1,1'-Binaphthalene]-1,1'(2H,2'H)-diol, 3,3',4,4'-tetrahydro--->1,2,3,4-tetrahydro-1-naphthyl hydroperoxide-->1,2,3,4-TETRAHYDRO-2-NAPHTHOL-->1,2-DIHYDRONAPHTHALENE | [Preparation Products]
Brodifacoum-->Flocoumafen-->Coumatetralyl-->5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid-->8-BROMO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE-->(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL-->5,6,7,8-TETRAHYDRO-1-NAPHTHOL-->2,3,4,5-Tetrahydro-1H-benzo[b]azepine-->1,2,3,4-Tetrahydro-1-naphthylamine-->2,3-Dihydro-1,4-naphthoquinone-->(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
| Hazard Information | Back Directory | [Chemical Properties]
clear colourless to slightly brown viscous liquid | [Uses]
1,2,3,4-Tetrahydro-1-naphthol was used as chiral probe to examine the role of three aromatic residues in enzyme-substrate interactions at the sulfuryl acceptor binding site of aryl sulfotransferase IV enzyme. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c | [General Description]
(R)-(-)-enantiomer of 1,2,3,4-Tetrahydro-1-naphthol is a substrate for aryl sulfotransferase (AST) IV enzyme and (S)-(+)-1,2,3,4-tetrahydro-1-naphthol is a competitive inhibitor of AST IV-catalyzed sulfation of 1-naphthalenemethanol. It is the major urinary metabolite of tetralin. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
1,2,3,4-Tetrahydro-1-naphthol(529-33-9)MS
1,2,3,4-Tetrahydro-1-naphthol(529-33-9)1HNMR
1,2,3,4-Tetrahydro-1-naphthol(529-33-9)13CNMR
1,2,3,4-Tetrahydro-1-naphthol(529-33-9)IR1
1,2,3,4-Tetrahydro-1-naphthol(529-33-9)Raman
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