ChemicalBook--->CAS DataBase List--->53267-01-9

53267-01-9

53267-01-9 Structure

53267-01-9 Structure
IdentificationBack Directory
[Name]

Cibenzoline
[CAS]

53267-01-9
[Synonyms]

Exacor
Cibenol
UP 33-901
Cifenline
Moracizin
Ro 22-7796
CIBENZOLINE
Cibenzolina
Cibenzolinum
Cibenzoline D4
Cibenzoline D5
(RS)-Cibenzoline
Cibenzoline USP/EP/BP
Cibenzolinum [inn-latin]
Cibenzolina [inn-spanish]
2-(2,2-Diphenylcyclopropyl)-2-imidazoline
2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
1H-Imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-
cibenzoline:2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-IMIDAZOLE
[EINECS(EC#)]

258-453-7
[Molecular Formula]

C18H18N2
[MDL Number]

MFCD00864706
[MOL File]

53267-01-9.mol
[Molecular Weight]

262.35
Chemical PropertiesBack Directory
[Melting point ]

103-104°
[Boiling point ]

449.2±45.0 °C(Predicted)
[density ]

1.17±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

10.82±0.40(Predicted)
[color ]

White to Pale Yellow
[CAS DataBase Reference]

53267-01-9
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acrylonitrile-->Ethylenediamine-->Diphenyldiazomethane
Hazard InformationBack Directory
[Description]

Cibenzoline is a structurally novel, class I (quinidine-like) antiarrhythmic agent. It has additional properties of class III and class IV compounds, delaying repolarization and antagonizing the positive inotropic effects of calcium.
[Chemical Properties]

Crystallized from petroleum ether, melting point 103-104°C. Acute toxicity LD50 (mg/kg): 64 by intravenous injection. Cibenzoline Suecinate: C18H18N2?C4H6O4. [10067-32-8]. Crystallized from ethanol-ether, melting point 165°C.
[Originator]

Hexachemie (France)
[Uses]

Cardiac depressant.
[Definition]

ChEBI: Cibenzoline is a diarylmethane.
[Brand name]

CIPRALAN
[storage]

Store at -20°C
Safety DataBack Directory
[Toxicity]

LD100 in rats (mg/kg): 64 i.v. (Cognaco)
Spectrum DetailBack Directory
[Spectrum Detail]

Cibenzoline(53267-01-9)IR1
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