| Identification | Back Directory | [Name]
8-iso-16-cyclohexyl-tetranor Prostaglandin E2 | [CAS]
53319-30-5 | [Synonyms]
8-iso-16-cyclohexyl-tetranor Prostaglandin E2
5-Heptenoic acid, 7-[2-(4-cyclohexyl-3-hydroxy-1-butenyl)-3-hydroxy-5-oxocyclopentyl]-, [1R-[1α(Z),2β(1E,3R*),3α]]- (9CI) | [Molecular Formula]
C22H34O5 | [MDL Number]
MFCD12912331 | [MOL File]
53319-30-5.mol | [Molecular Weight]
378.5 |
| Chemical Properties | Back Directory | [Boiling point ]
566.998±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.171±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml | [pka]
4.754±0.10(predicted) |
| Hazard Information | Back Directory | [Description]
8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from polyunsaturated fatty acids during lipid peroxidation.1 8-iso-16-cyclohexyl-tetranor PGE2 is a synthetic analog of 8-iso PGE2. There are no published studies on the pharmacological properties of 8-iso-16-cyclohexyl-tetranor PGE2. | [Uses]
8-Iso-16-cyclohexyl-tetranor prostaglandin E2 is an analog of Prostaglandin E2 (HY-101952)[1]. | [References]
1. Morrow, J.D., Minton, T.A., Mukundan, C.R., et al. Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes J. Biol. Chem. 269,4317-4326(1994). |
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