| Identification | Back Directory | [Name]
Isogosferol | [CAS]
53319-52-1 | [Synonyms]
Isogosferol
Isogospherol
9-(2-hydroxy-3-methylbut-3-enoxy)furo[3,2-g]chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2R)-2-hydroxy-3-methyl-3-buten-1-yl]oxy]- | [Molecular Formula]
C16H14O5 | [MDL Number]
MFCD20260624 | [MOL File]
53319-52-1.mol | [Molecular Weight]
286.28 |
| Chemical Properties | Back Directory | [Melting point ]
72-73.5 °C | [Boiling point ]
498.197±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.320±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
13.279±0.20(predicted) |
| Hazard Information | Back Directory | [Description]
Isogosferol is a minor furocoumarin of Murraya koenigii seeds. | [Uses]
Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2[1]. | [References]
[1] Song HY, et al. Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from Citrus junos Seed Shells through Bioactivity-Guided Fractionation. Molecules. 2019 Nov 12;24(22):4088. DOI:10.3390/molecules24224088 |
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