| Identification | Back Directory | [Name]
2'-MONOPHOSPHOADENOSINE 5'-*DIPHOSPHORIBOSE SODIUM | [CAS]
53595-18-9 | [Synonyms]
ATP-Ribose
2'-Phosphoadenosine diphosphoribose
Adenosine-5'-O-diphosphoribose phosphate
Adenosine 2'-phosphate 5'-diphosphoribose
2'-Phosphoadenosine 5'-diphosphate ribose
Adenosine 2'-monophospho-5'-diphosphoribose
2'-monophosphoadenosine 5'-*diphosphoribose sodiu
2'-MONOPHOSPHOADENOSINE 5'-*DIPHOSPHORIBOSE SODIUM
2μ-Monophosphoadenosine 5μ-diphosphoribose sodium salt
Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'→5-ester with D-ribose | [Molecular Formula]
C15H24N5O17P3 | [MDL Number]
MFCD00056997 | [MOL File]
53595-18-9.mol | [Molecular Weight]
639.3 |
| Hazard Information | Back Directory | [Uses]
ADPRP is an intranuclear enzyme whose main activity is to use NAD+ (nicotinamide adenine dinucleotide) as a substrate to add ADP-ribose units to chromatin-bound proteins, including the ADPRP enzyme itself. This process, called poly(ADP-ribosylation), is a post-translational modification that regulates the interaction between DNA and nuclear proteins[1]. | [References]
[1] Yamanaka H, et al. Human autoantibodies to poly (adenosine diphosphate-ribose) polymerase[J]. The Journal of clinical investigation, 1987, 80(3): 900-904. DOI:10.1172/JCI113150 |
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