| Identification | Back Directory | [Name]
NSC 403387 hydrochloride | [CAS]
5361-15-9 | [Synonyms]
GMQ hydrochloride
NSC 403387 hydrochloride
GMQ hydrochloride >=95% (HPLC)
2-GUANIDINO-4-METHYLQUINAZOLINE HYDROCHLORIDE
2-Guanidine-4-methylquinazoline hydrochloride
4-Methyl-2-guanidino quinazoline hydrochloride
1-(4-Methylquinazolin-2-yl)guanidine hydrochloride
N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride | [Molecular Formula]
C10H12ClN5 | [MDL Number]
MFCD00035249 | [MOL File]
5361-15-9.mol | [Molecular Weight]
237.69 |
| Chemical Properties | Back Directory | [Melting point ]
328-330 °C | [storage temp. ]
room temp | [solubility ]
DMSO: soluble2mg/mL, clear (warmed) | [form ]
powder | [color ]
white to beige | [InChI]
1S/C10H11N5.ClH/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12;/h2-5H,1H3,(H4,11,12,13,14,15);1H | [InChIKey]
VNPZWQRWOHFAPD-UHFFFAOYSA-N | [SMILES]
CC1=NC(NC(N)=N)=NC2=C1C=CC=C2.Cl |
| Hazard Information | Back Directory | [Uses]
GMQ Hydrochloride is a selective ASIC3 opener. | [Biological Activity]
GMQ/2-Guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC) th at activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH dependence for activation and inactivation. |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|