| Identification | Back Directory | [Name]
Onitin | [CAS]
53823-02-2 | [Synonyms]
Onitin
Golden fern Pavilion
4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-3H-inden-1-one
2,3-Dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-inden-1-one
1H-Inden-1-one,2,3-dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetraMethyl- | [Molecular Formula]
C15H20O3 | [MDL Number]
MFCD09837966 | [MOL File]
53823-02-2.mol | [Molecular Weight]
248.32 |
| Chemical Properties | Back Directory | [Melting point ]
212 °C | [Boiling point ]
445.3±45.0 °C(Predicted) | [density ]
1.156±0.06 g/cm3(Predicted) | [pka]
9.76±0.40(Predicted) | [LogP]
2.920 (est) |
| Hazard Information | Back Directory | [Uses]
Onitin is a natural product, that can be isolated from Onychium siliculosum. Onitin is also a non-competitive antagonist of histamine. Onitin shows activity in blocking the peristaltic reflex of the guinea-pig ileum, in inhibition of the responses of guinea-pig ileum to histamine and of inhibition of the responses of guinea-pig tracheal muscle to histamine[1]. | [References]
[1] Wu T S, et al. Flavanone and other constituents from Onychium siliculosum. Phytochemistry, 1981, 20(3):527–529. |
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