| Identification | Back Directory | [Name]
CINANSERIN HYDROCHLORIDE | [CAS]
54-84-2 | [Synonyms]
DPTC
maptc
sq10,643
Nsc125717
CINANSERIN
Cinnanserin
DPTC HYDROCHLORIDE
CINANSERIN HYDROCHLORIDE
2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE
DPTC 2'-(3-Dimethylaminopropylthio)cinnamanilide hydrochloride
2’-((3-(dimethylamino)propyl)thio)-cinnamanilidmonohydrochloride
2'-[[3-(Dimethylamino)propyl]thio]cinnamanilide monohydrochloride
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE
Cinnamanilide, 2'-[[3-(dimethylamino)propyl]thio]-, monohydrochloride
(E)-N-[2-[3-(dimethylamino)propylsulfanyl]phenyl]-3-phenylprop-2-enamide
n-(2-((3-(dimethylamino)propyl)thio)phenyl)-3-phenyl-2-propenamidmonohyd
N-(2-((3-(Dimethylamino)propyl)thio)phenyl)-3-phenylacrylamide hydrochloride
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE
2-Propenamide, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-, monohydrochloride | [Molecular Formula]
C20H25ClN2OS | [MDL Number]
MFCD00055609 | [MOL File]
54-84-2.mol | [Molecular Weight]
376.94 |
| Chemical Properties | Back Directory | [density ]
1.22 g/cm3 | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO : 125 mg/mL (331.62 mM; Need ultrasonic) | [form ]
Powder | [color ]
Light yellow to yellow | [Water Solubility ]
Soluble to 50 mM in water |
| Hazard Information | Back Directory | [Uses]
Serotonin
inhibitor. | [Application]
Cinanserin Hydrochloride is a useful research chemical. Cinanserin is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. | [Definition]
ChEBI: Cinanserin hydrochloride is the hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro. It has a role as an antiviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an anticoronaviral agent. It contains a cinanserin(1+). | [in vivo]
Cinanserin (5 mg/kg; intravenous injection; for 2 hours; male Wistar rats) treatment significantly reduces systemic burn edema to shamburn levels. Leukocyte-endothelial interactions are significantly reduced by administration of Cinanserin[2]. | Animal Model: | Male Wistar rats (250 g) underwent thermal injury[2] | | Dosage: | 5 mg/kg | | Administration: | Intravenous injection; for 2 hours | | Result: | Significantly reduced systemic burn edema to shamburn levels..
|
| [IC 50]
5-HT2 Receptor: 41 nM (Ki); 3C-like proteinase | [storage]
Desiccate at RT |
|
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BOC Sciences
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Energy Chemical
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