ChemicalBook--->CAS DataBase List--->54081-48-0

54081-48-0

54081-48-0 Structure

54081-48-0 Structure
IdentificationBack Directory
[Name]

Isoastilbin
[CAS]

54081-48-0
[Synonyms]

Isoastilbin
4H-1-Benzopyran-4-one,3-[(6-deoxy-R-Lmannopyranosyl) oxy]-2-(3,4-dihydroxyphenyl)- 2,3-dihydro-5,7-dihydroxy-,(2R,3S)-
4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3S)-
[Molecular Formula]

C21H22O11
[MOL File]

54081-48-0.mol
[Molecular Weight]

450.39
Chemical PropertiesBack Directory
[Melting point ]

278-280 °C (decomp)
[Boiling point ]

801.1±65.0 °C(Predicted)
[density ]

1.74±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[pka]

7.34±0.60(Predicted)
[CAS DataBase Reference]

54081-48-0
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

Isoastilbin (IA) is a dihydroflavonol glycoside compound, and studies have shown that IA has a good effect on antioxidants.
[Biological Activity]

Isoastilbin, a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. It inhibits glucosyltransferase (GTase) with IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. It has neuroprotective, antioxidant, antimicrobial and anti-apoptotic properties and can be used in Alzheimer's disease research.
[target]

IC50: 54.3 μg/mL (Glucosyltransferase (GTase)

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