| Identification | Back Directory | [Name]
CIVETONE | [CAS]
542-46-1 | [Synonyms]
Zibeton
CIVETONE
civetton
FEMA 3425
Ai3-38745
Brn 1954923
(Z)-Civetone
cis-Civetone
10-Oxocycloheptadecene
10-Ketocycloheptadecene
9-CYCLOHEPTADECEN-1-ONE
CYCLOHEPTADECA-9-EN-1-ONE
(Z)-Cycloheptadec-9-enone
(z)-9-cycloheptadecen-1-on
(Z)-9-Cycloheptadecen-1-one
cis-9-cycloheptadecen-1-one
9-Cycloheptadecen-1-one,(Z)-
(9Z)-9-Cycloheptadecene-1-one
9-Cycloheptadecen-1-one, cis-
(9Z)-cycloheptadec-9-en-1-one
9-Cycloheptadecen-1-one, (9Z)- | [EINECS(EC#)]
208-813-4 | [Molecular Formula]
C17H30O | [MDL Number]
MFCD00053257 | [MOL File]
542-46-1.mol | [Molecular Weight]
250.42 |
| Hazard Information | Back Directory | [Definition]
ChEBI: A macrocycle that is cycloheptadecanone with an unsaturation at position 9 (the 9Z-stereoisomer). It has been found in African Civets. | [Uses]
In perfumery. | [Chemical Properties]
CIVETONE is a colorless
liquid with warm, sensual, animalic musky odor and extreme tenacity. It is
themain odoriferous constituent of civet.Civetonewas formerly prepared bymultistep
syntheses, for example. Recently, newer processes using dimethyl
(Z)-9-octadecendioate as starting material have been described. This is cyclized
by a Dieckmann condensation either in liquid or in gaseous phase.
(Z)-9-Octadecendioic acid is available by microbial oxidation of oleic acid with
Candida tropicalis.
It is used in fine fragrance compositions for, for example, toiletries and body
care products. | [Chemical Properties]
Cycloheptadeca-9-en-1-one has an obnoxious animal-gland odor. It can be pleasant at extreme dilutions. | [Occurrence]
In civet (cis-form). | [Preparation]
From aleuritic acid, the trans- form only; the cis- and trans-forms from ethyl-9-keto heptadecanedioate. | [Aroma threshold values]
Detection: 3 ppb |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
38 | [Safety Statements ]
36/37 | [TSCA ]
TSCA listed | [Safety Profile]
A skin irritant. When
heated to decomposition it emits acrid
smoke and irritating fumes. | [Toxicity]
The acute oral LD50 value in rats was reported as > 5 g/kg and the acute dermal LD50 value in rabbits exceeded 2 g/kg (Moreno. 1974). |
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