| Identification | More | [Name]
6-AMINO-2-METHYL-2-HEPTANOL HYDROCHLORIDE | [CAS]
543-15-7 | [Synonyms]
6-AMINO-2-METHYL-2-HEPTANOL HCL
6-AMINO-2-METHYL-2-HEPTANOL HYDROCHLORIDE
HEPTAMINOL HYDROCHLORIDE
TIMTEC-BB SBB003737
2-methyl-6-amino-2-heptanolhydrochloride
6-amino-2-methyl-2-heptanohydrochloride
6-hydroxy-6-methyl-2-heptylaminhydrochloride
6-methyl-2-amino-6-heptanolhydrochloride
cardiosintol
cortensor
ea-85
heptamylhydrochloride
HeptaminolHCl
6-Amino-2-methyl-2-heptanol hydrochloride, 98+%
2-Heptanol, 6-amino-2-methyl-, hydrochloride
6-Amino-2-methyl-2-heptanol, Heptaminol hydrochloride | [EINECS(EC#)]
208-837-5 | [Molecular Formula]
C8H20ClNO | [MDL Number]
MFCD00013015 | [Molecular Weight]
181.7 | [MOL File]
543-15-7.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE CRYSTALLINE POWDER | [Melting point ]
165-167 °C(lit.)
| [storage temp. ]
Store at -20°C | [solubility ]
Freely soluble in water, soluble in alcohol, practically insoluble in methylene chloride. | [form ]
neat | [color ]
White to off-white | [Sensitive ]
Hygroscopic | [Merck ]
14,4657 | [BRN ]
3673011 | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H | [InChIKey]
JZNBMCOSOXIZJB-UHFFFAOYSA-N | [SMILES]
Cl.CC(N)CCCC(C)(C)O | [CAS DataBase Reference]
543-15-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
MJ3240000
| [Storage Class]
11 - Combustible Solids | [Toxicity]
LD50 intraperitoneal in mouse: 900mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white, crystalline powder | [Uses]
Antihypotensive | [Uses]
Heptaminol Hydrochloride is used in the preparation of drugs for treating cardiovascular and cerebrovascular diseases. | [in vivo]
Heptaminol hydrochloride (12 μL; 50% water/acetone) stimulates NO synthesis from constitutive NOS and attenuates TPA-induced depletion of NK cells at the edge of the mouse ear. Heptaminol hydrochloride exerts anti-proliferative and anti-inflammatory effects on TPA, suggesting important anti-tumor function[2].
| Animal Model: | Acute TPA-induced inflammatory ear skin changes in Balb/c mouse (5-7 wk)[2] | | Dosage: | 2.5 nmol Heptaminol in 12 μL | | Administration: | Topical treatment for single dose; Heptaminol was dissolved in 50% water/acetone; 30 min before 0.4 nmol TPA (in 12 μL acetone) treatment. | | Result: | Stimulated NO production and directly inhibits tumors caused by TPA promoting inflammation.
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