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543-15-7

543-15-7 Structure

543-15-7 Structure
IdentificationMore
[Name]

6-AMINO-2-METHYL-2-HEPTANOL HYDROCHLORIDE
[CAS]

543-15-7
[Synonyms]

6-AMINO-2-METHYL-2-HEPTANOL HCL
6-AMINO-2-METHYL-2-HEPTANOL HYDROCHLORIDE
HEPTAMINOL HYDROCHLORIDE
TIMTEC-BB SBB003737
2-methyl-6-amino-2-heptanolhydrochloride
6-amino-2-methyl-2-heptanohydrochloride
6-hydroxy-6-methyl-2-heptylaminhydrochloride
6-methyl-2-amino-6-heptanolhydrochloride
cardiosintol
cortensor
ea-85
heptamylhydrochloride
HeptaminolHCl
6-Amino-2-methyl-2-heptanol hydrochloride, 98+%
2-Heptanol, 6-amino-2-methyl-, hydrochloride
6-Amino-2-methyl-2-heptanol, Heptaminol hydrochloride
[EINECS(EC#)]

208-837-5
[Molecular Formula]

C8H20ClNO
[MDL Number]

MFCD00013015
[Molecular Weight]

181.7
[MOL File]

543-15-7.mol
Chemical PropertiesBack Directory
[Appearance]

WHITE CRYSTALLINE POWDER
[Melting point ]

165-167 °C(lit.)
[storage temp. ]

Store at -20°C
[solubility ]

Freely soluble in water, soluble in alcohol, practically insoluble in methylene chloride.
[form ]

neat
[color ]

White to off-white
[Sensitive ]

Hygroscopic
[Merck ]

14,4657
[BRN ]

3673011
[Major Application]

pharmaceutical (small molecule)
[InChI]

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H
[InChIKey]

JZNBMCOSOXIZJB-UHFFFAOYSA-N
[SMILES]

Cl.CC(N)CCCC(C)(C)O
[CAS DataBase Reference]

543-15-7(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[RTECS ]

MJ3240000
[Storage Class]

11 - Combustible Solids
[Toxicity]

LD50 intraperitoneal in mouse: 900mg/kg
Hazard InformationBack Directory
[Chemical Properties]

White or almost white, crystalline powder
[Uses]

Antihypotensive
[Uses]

Heptaminol Hydrochloride is used in the preparation of drugs for treating cardiovascular and cerebrovascular diseases.
[in vivo]

Heptaminol hydrochloride (12 μL; 50% water/acetone) stimulates NO synthesis from constitutive NOS and attenuates TPA-induced depletion of NK cells at the edge of the mouse ear. Heptaminol hydrochloride exerts anti-proliferative and anti-inflammatory effects on TPA, suggesting important anti-tumor function[2].

Animal Model:Acute TPA-induced inflammatory ear skin changes in Balb/c mouse (5-7 wk)[2]
Dosage:2.5 nmol Heptaminol in 12 μL
Administration:Topical treatment for single dose; Heptaminol was dissolved in 50% water/acetone; 30 min before 0.4 nmol TPA (in 12 μL acetone) treatment.
Result:Stimulated NO production and directly inhibits tumors caused by TPA promoting inflammation.
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

6-Amino-2-methyl-2-heptanol hydrochloride, 99%(543-15-7)
[Sigma Aldrich]

543-15-7(sigmaaldrich)
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