| Identification | Back Directory | [Name]
POLYGUANYLIC ACID (5') POTASSIUM SALT | [CAS]
54684-83-2 | [Synonyms]
POLY[G] POTASSIUM SALT
POLYGUANYLIC ACID POTASSIUM SALT
polyguanylic acid (5') potassium
POLYGUANYLIC ACID (5') POTASSIUM SALT
Polyguanylic acid potassium salt lyophilized powder | [Molecular Formula]
C10H14N5O8P | [MDL Number]
MFCD00131976 | [MOL File]
54684-83-2.mol | [Molecular Weight]
363.22 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
lyophilized powder | [biological source]
enzyme from (synthesis) | [Water Solubility ]
water: 19.60-20.40mg/mL, clear to slightly hazy, colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Polyguanylic acid potassium salt has been used:
- as a ligand for surface neuropilin-1 (NRP1) for internalization studies
- for intercalation studies with trisubstituted and disubstituted triazole-linked phenyl derivatives CL41, CL42 and CL2r50 using voltammetry method
- as a synthetic polynucleotide for agarose gel electrophoresis analysis
| [General Description]
Polyguanylic acid takes up a four-stranded helical structure. It is synthetically produced in Thermus thermophilus from guanosine diphosphate (GDP) and its synthesis is catalyzed by the enzyme polynucleotide phosphorylase. | [Biochem/physiol Actions]
Polyguanylic acid acts as a ligand for scavenger receptor and reduces the surface expression neuropilin-1 in endothelial cells. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1701258/0_EN.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Carbosynth
|
| Tel: |
+86 512 6260 5585 |
| Website: |
www.carbosynth.com |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|